Eastbourne Borough's 14-match unbeaten run came to an end when they were beaten 3-1 at Sutton.
Two goals in as many minutes in the first half undid Borough as their hopes of a South play-off place faded.
Borough had much the best of the opening play and a tremendous effort from Allan Tait, 25 yards out on the right, was only fractionally wide of the far post in the 13th minute.
Minutes later Adam Wilde should have scored when he scooped Scott Ramsay's flick-on over the bar from 12 yards.
Borough were stunned as Sutton struck twice in two minutes against the run of play. In the 26th minute, Warren McBean raced on to a long ball down the middle and confidently drove past keeper Lee Hook.
Two minutes later McBean cut inside on the right and somehow got past Hook before squaring back for Bashiru Alimi to poke into an empty net.
Marc Pullan hobbled off at the start of the second half but Borough got back into the game in the 51st minute. Wilde's corner from the left was headed back for Tait to turn into the net.
Borough piled on the pressure in a bid for an equaliser and the Sutton goal had numerous narrow escapes.
But it was Sutton who had the last word and ironically it was former Borough player John Scarborough who sealed victory for the home side when he powerfully headed Matt Gray's corner into the roof of the net in the 78th minute.
A goal in each half by Jean-Michel Sigere was enough to earn Lewes a 2-0 home win against relegation threatened Hayes.
A dour and at times overly physical first half hour offered little by way of goalmouth action and until Sigere latched on to a Lewis Hamilton through ball and fired a low drive from just inside the area past visiting keeper Kevin Davies.
Sigere got his second with 20 minutes remaining, releasing substitute Simon Wormull down the left flank with an inch-perfect pass before continuing his run to head home the midfielder's cross from close range.
Luke Nightingale got a 51st-minute leveller as Bognor drew 1-1 at Thurrock.
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