Son Heung-min is “unlikely” to be available for Spurs as they visit the Amex.
The South Korea international was substituted with a hamstring injury during last week’s Europa League clash with Qarabag and has since missed wins over Manchester United and Ferencvaros.
Timo Werner could be in line for another start in place of the injured Son for Postecoglou’s team, who have won five successive matches in all competitions.
Postecoglou said: “Destiny (Udogie), we think will be OK. We train today and tomorrow, so he has to get through that.
“Sonny is unlikely, he’s pushing hard, but the turnaround might be too quick for him to be available at this stage.”
Son has two goals and four assists in his 14 games against Albion, which have brought nine Tottenham wins.
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