Kaoru Mitoma has been ruled out for up to six weeks.
The Albion winger suffered an ankle injury in the 1-1 draw at Crystal Palace.
He is one of ten players who cannot start the home game against Tottenham.
Two of them could be available to come off the bench, including Pervis Estupinan.
The Ecuador left-back has been out for three months, bar a brief and unsuccessful attempt to return at Ajax.
Comments: Our rules
We want our comments to be a lively and valuable part of our community - a place where readers can debate and engage with the most important local issues. The ability to comment on our stories is a privilege, not a right, however, and that privilege may be withdrawn if it is abused or misused.
Please report any comments that break our rules.
Read the rules here