Albion have made seven personnel changes for the Capital One Cup – and handed first starts to two players.
Rohan Ince makes his debut and Kemy Agustien gets his first start in a midfield trio which also includes Jake Forster-Caskey.
Casper Ankergren keeps goal in the first round tie at home to Newport County.
There is also a positonal change for one of the four players who remains in the side which kicked off at Elland Road.
That concerns David Lopez, the midfielder who fills in at right-back tonight.
Oscar Garcia also brings in Adam El-Abd, Will Buckley and Kazenga LuaLua.
Newport come into their first League Cup tie in 26 years on a high after beating Accrington in League Two on Saturday.
Christian Jolley and Chris Zebroski form the strike pairing in their 3-5-2 set-up.
Albion: Ankergren; David Lopez, Greer, El-Abd, Calderon; Ince, Agustien, Forster-Caskey; Buckley, LuaLua, Barnes. Subs: Kuszczak, Dunk, Ulloa, Upson, Bridcutt, March, Maksimenko.
Newport: Stephens; Yakubu, Anthony, Worley; Jackson, Minshull, Chapman, Willmott, Sandell; Zebroski, Jolley. Subs: Bitnner, Pipe, Hughes, Porter, Crow, Washington.
Ref: Brendan Malone (Wiltshire)
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