Sussex students are to take part in the creation of a national virtual science classroom which will be shared by colleges across the country.
They will watch BBC presenters stage the world's first schools science demonstration to be broadcast on the internet early next month.
Students from the College of Richard Collyer in Horsham, Christ's Hospital Sixth Form and the Weald School in Billinghurst will travel to the Royal Institution in London for the September 5 event.
They will see Adam Hart-Davis of the Local Heroes science programmes front two 'e-classroom' broadcasts.
Mr Hart-Davis will be joined by Professor Susan Greenfield of the Brain Story series.
Meanwhile, students at Varndean College in Brighton will watch the show on the net.
More than 90 schools from across the United Kingdom are expected to log on to the demonstrations, which have been pioneered by the Novartis drug company.
Julia Hatto, a research scientist at Novartis' Horsham laboratories, is co-ordinating the colleges' involvement.
She said: "It's important all schools get a chance to see this sort of thing."
Nick Baker, head of science at the College of Richard Collyer, said: "It will be very useful for our students."
The Novartis demonstrations will cover DNA replication and pollution-free energy.
Both will be targeted at first year A-level students and relate to National Curriculum topics.
Mr Hart-Davies said: "This will be the first time I've broadcast over the internet and I'm delighted to be encouraging online science teaching."
Junior education minister Michael Wills said the project showed how technology could make science entertaining.
Mr Wills said: "The e-Classroom initiative from Novartis is an excellent example of harnessing technology to make education entertaining and exciting.
"We hope schools up and down the country will embrace the internet broadcast and enjoy watching the demonstrations."
The internet is becoming increasingly important in education. Educational websites such as Schoolsnet now offer a mass of National Curriculum-related learning material.
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