Hundreds of campaigners are expected to take to the streets of Crawley calling for a new hospital to be built.
At least 700 people are set to march in protest at a decision not to build a hospital at Pease Pottage.
Residents are invited to join the protest from 11am on February 22.
It is expected to be attended by the mayor of Crawley, Les Hench, as well as other councillors and members of the Crawley Hospital Campaign.
Protesters will meet in the Crawley Labour Supporters' Club car park, Ifield Avenue, West Green.
They will pass Crawley Hospital in West Green and march around the town, ending in Queen's Square at about 1pm.
The event has been organised by the Crawley Labour Party and the Crawley Hospital Campaign.
Robert Hull, party chairman for Crawley Labour Party, said: "This is not a party political event, this is about getting a new hospital for all the people of Crawley. I invite everyone who wants a new hospital to join us on this march."
The march has been organised following last month's decision by health chiefs to block a proposal for a hospital at Pease Pottage.
The board voted to turn East Surrey Hospital in Redhill into the main hospital for north Sussex and south-east Surrey, while developing some services at Crawley.
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