Albion stayed on course for Division One with their fifth straight home win against promotion rivals Huddersfield.
Junior Lewis was the hero on 54 minutes with his second goal in as many full appearances since a loan move from Leicester.
It means Peter Taylor's Seagulls have closed the gap on leaders Reading to just two points and they still have a game in hand.
Lewis has already made quite an impact since his debut as a late substitute at Oldham last Saturday.
The lanky midfielder rounded off Monday's 3-1 triumph against Reading and he demonstrated again the value of a player getting forward from the centre of the park.
Lewis headed in a left-wing cross by the influential Paul Brooker to end Huddersfield's seven-match unbeaten League run.
It was hard work for both sides on a heavy Withdean pitch, but Albion deserved the points in front of another sell-out crowd of 6,744.
They always looked the more menacing side, with Brooker involved in most of their best moments.
Huddersfield rarely threatened as they suffered only their second defeat in 18 League games.
Zamora was rather harshly booked in the closing stages for deliberately heading the ball back into touch, which was interpreted as time-wasting by referee Steve Bennett.
Zamora begins a three-match ban in next Saturday's visit by Wrexham.
That also marks the start of a two-match suspension for fellow striker Daniel Webb, a substitute today.
Albion are now six points clear of their pursuers for the second automatic promotion place and nine ahead of Huddersfield.
Bristol City have moved into third place after a 3-0 home win against Oldham, above Stoke on goal difference after the Potteries club were held to a 0-0 draw at next-to-bottom Notts County.
Comments: Our rules
We want our comments to be a lively and valuable part of our community - a place where readers can debate and engage with the most important local issues. The ability to comment on our stories is a privilege, not a right, however, and that privilege may be withdrawn if it is abused or misused.
Please report any comments that break our rules.
Read the rules hereComments are closed on this article