Damian Webber scored a hat-trick as Southwick gave caretaker boss Mick Fogden a winning start with a 4-0 success at Arundel.
Webber's treble was completed by a penalty and Tony Holden also found the net in a comfortable success.
Former Southwick boss Sammy Donnelly is still looking for his first win at Three Bridges following a 2-1 reverse at Whitehawk.
Pat Massaro's first half penalty put Bridges ahead but Hawks hit back in the final 20 minutes through Jamie Lambert and Simon Rowland.
Champions Burgess Hill beat Sidley United 2-1 with goals from Sean Edwards and Nick Sullivan. Mark Funnell replied.
Simon Clayton got the only goal as East Preston beat Selsey 1-0.
In division two, Rye and Iden United maintained their title challenge with a 1-0 win at Steyning thanks to Michael O'Callaghan's 15th minute strike.
Ramin Jarvand scored all four as Broadbridge Heath beat Oving 4-1.
Results, division one: Arundel 0 Southwick 4 (Webber 17, 61, 70pen, Holden 30), Burgess Hill 2 (Edwards 35, Sullivan 42) Sidley 1 (Funnell 88), East Preston 1 (Clayton 83) Selsey 0, Whitehawk 2 (Lambert 72, Rowland 85) Three Bridges 1 (Massaro 43pen).
Division two: Broadbridge Heath 4 (Jarvand 6, 48, 60, 82) Oving 1 (Smith 64), Steyning Town 0 Rye and Iden United 1 (O'Callaghan 85).
Division three: Storrington 0 Hurstpierpoint 3 (Swain 10, Kempton 17, Biggs 80).
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