Reigning champions Withdean 2000 had Jay Pickering sent off as they opened their Combined Counties League campaign with a 3-0 defeat at home to Westfield.
Shaun Grice had four good chances in a second half, which Withdean controlled, but by then they were already two goals behind.
Coach Bob Hitchcock said: "We are going with youngsters this year and it will be a learning process."
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