Police seized drugs and stolen property in a series of raids.
Cocaine worth hundreds of pounds was found when drugs squad officers searched a house in Harmsworth Crescent, Hove.
Two men were later arrested, one at a nearby property and the second at an address in East Brighton.
Both were held on suspicion of possessing a class A drug with intent to supply.
They were released on police bail while investigations continue.
A small amount of what was believed to be cannabis and cocaine was found at a house in Stonery Close, Portslade, after a separate raid.
Jewellery and electrical items believed to have been stolen in burglaries in the last week were also discovered at the house.
A 17-year-old youth was released on bail to return to Hove police station at a later date.
Inspector Jason Hazzard, who is in charge of neighbourhood policing in Hove and Portslade, said: “This is potentially a very good result for us.
“We are determined to take action against people suspected of supplying Class A drugs in the area.
“We rely on people to act as our eyes and ears in the community and to report any suspicious activity to us.”
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