Police are still at the scene of a suspected attempted murder.
A semi-detached house in Rymill Road, St Leonards, was cordoned off after a man was taken to hospital with serious injuries.
Sussex Police went to the property in response to a report of serious assault at around 5.39pm on Monday.
The man, in his 40s and from St Leonards, is in a stable condition.
Police have arrested a man and a woman on suspicion of attempted murder.
A spokeswoman for Sussex Police said: "This is being treated as an isolated incident, all parties are believed to be known to one another and no other persons are being sought at this time.
“The public can expect to see an increased police presence in the area as our enquiries continue.
“Anyone with any information is asked to report it online or call 101, quoting serial 991 of 11/11.”
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