Albion will be running its own bus shuttle service to get fans to the game due to crippling train strikes.
Train driver strikes announced last week mean there are no trains running to Falmer station for the Premier League fixture against Brentford this Wednesday.
Albion will run a shuttle service from 4.30pm, three hours before kick-off, from Old Steine in Brighton and Lewes railway station.
The Old Steine service will depart from bus stop F. Supporters can also use Brighton and Hove Buses number 25, 28 and 29 to Falmer. After the match, it departs from the Falmer station A27 bus stop.
For the Lewes shuttle after the match, people need to go to the A27 eastbound bus stop.
The Mill Road and Brighton Racecourse sites open from 4.30pm and are on a first-come, first-serve basis.
The EDF site in Hove and Pyecombe Equestrian Centre sites are pay in advance but have already sold out.
The last park-and-ride buses leave one and a half hours after the final whistle.
Albion also recommended booking a coach seat with Seagull Travel which provides pick-up locations across Sussex, Kent and Surrey.
There is a drop-off and pick-up point located at Sussex University car park 5 by the Sports Hall, using the underpass to walk to The Amex. There are no stopping locations along Village Way or Woollards Way.
Govia Thameslink Railway confirmed to The Argus last week that no trains would run to Falmer.
A spokesman said: "Regrettably, our advice for fans is to consider alternative ways to reach these matches.
“On December 6, there will be no trains to the match. On December 9, when there is also engineering work closing the line west of Brighton (Brighton to Littlehampton), we will have far fewer trains and fans will risk missing the start of the match if they take the train.
“They should plan ahead carefully and give themselves plenty of extra time to complete their journey because there will be queues and delays.
“We are working closely with the club which is passing this message on and looking at alternative travel arrangements."
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