Commuters have been advised to consider changing travel plans or working from home to avoid disruption caused by Storm Ciaran.
Gusts of up to 80mph and heavy downpours are forecast on Thursday, with weather warnings in place for both wind and rain for Sussex.
Train operators have urged passengers to consider changes to their journey due to the possibility of disruption or cancellation of services.
Speed restrictions will also be in place, which will cause delays to services.
A spokesman for Govia Thameslink Railway, which operates Southern, Thameslink and Gatwick Express services, said: “Storm Ciaran is expected to cause significant disruption to services across the South East on Thursday, with a risk of disruption into Friday too.
“At this point, there is still some uncertainty about the impact.
“However, Network Rail is planning for speed restrictions to be in place across the network, which will cause delays and lead to changes to the train service.
“Given the high winds that are forecast and the risk of fallen trees and debris being blown on the tracks, some routes may have to close on Thursday, so you should consider changing your travel plans or working from home on Thursday if you can.”
READ MORE: 'Danger to life': Second weather warning issued for Sussex ahead of Storm Ciaran
The Met Office has warned of a potential “danger to life”, with weather warnings in place for both wind and rain for Thursday.
The weather service has warned the storm could cause damage to buildings and power lines, as well as large waves and flying debris.
Met Office deputy chief meteorologist Steven Keates said: “Storm Ciaran will bring very strong winds along the south coast of England and Wales, with gusts of 70 to 80mph possible.
“Further inland, gusts could rush up to 50 or 60mph.
“As well as strong winds, this deep low-pressure system will bring heavy rain to many parts of the UK.
“The heaviest rain is expected in southern and western areas with 20 to 25mm possible widely and 40 to 60mm over higher ground.
“This rain will fall on already saturated ground, bringing a risk to flooding.”
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