A man has died and a woman has suffered life-threatening injuries in a two-car collision.

A large number of emergency services and an air ambulance team responded to the serious crash on the A264 near Rusper Road roundabout, Horsham, at around 7.20pm on Saturday.

Sussex Police have now confirmed that one of the drivers, a 49-year-old man from Broadbridge Heath, died at the scene.

The Argus: Emergency services at the A264Emergency services at the A264 (Image: Supplied)

A 52-year-old woman from Billingshurst is in a critical condition in hospital after suffering life-threatening injuries and a 55-year-old woman is also in a serious condition.

A Sussex Police spokeswoman said: “Police are appealing for witnesses following a fatal collision in Horsham.

“The collision, which involved two cars, happened on the A264 Rusper Road Roundabout at about 7.20pm on Saturday.

“Tragically, the driver of one of the vehicles, a 49-year-old man from Broadbridge Heath, died at the scene.

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“A 52-year-old woman from Billingshurst suffered life-threatening injuries in the collision and is in a critical condition in hospital.

“A 55-year-old woman from Billingshurst is also in a serious condition in hospital.

“A 17-year-old boy and a 17-year-old girl were treated at the scene for minor injuries but did not require hospital treatment.”

The Argus: Emergency services at the A264Emergency services at the A264 (Image: Supplied)

A section of the road was closed yesterday evening and into this morning. The road has since re-opened.

Investigating officers are keen to speak to anyone who witnessed the collision or saw the two vehicles, a white BMW X5 and a black BMW 1 Series, being driven in the area beforehand.

Anyone with information is asked to contact Sussex Police online or by calling 101 quoting Operation Temperature.