Pictures show the aftermath of a fatal stabbing.
Sussex Police received a report of a stabbing in Malthouse Road, close to Crawley railway station, at 3.21pm on Monday.
An 18-year-old man was found with serious injuries and despite the best efforts of members of the public and paramedics, who commenced CPR, he was pronounced dead at the scene.
His next of kin have been informed and are receiving support.
Officers carried out an extensive search of the area, assisted by the National Police Air Service helicopter, and a 17-year-old male from Worthing and an 18-year-old male from Horsham were arrested on suspicion of murder.
An 18-year-old female from Crawley has also been arrested for assisting an offender.
Pictures and video from the scene show a heavy police presence in the street with a cordon and blue tent in place.
Forensics teams can be seen working in the area.
Sussex Police have appealed for any witnesses to come forward.
Detective Chief Inspector Debbie White said: “This is a fast-moving investigation, and we are asking anyone with any information about the incident to please come forward.
“We are treating this as an isolated incident with no threat to the wider community, however the public can expect to see an increased police presence in the area this evening as our enquiries continue.
“In the meantime, we would urge the public to refrain from speculating around the circumstances.
“Our thoughts remain with the victim’s family at this difficult time, and we are determined to find those responsible for this tragic crime and bring them to justice.”
People can report any information online or by calling 101, quoting Operation Gateford.
People can also contact the independent charity Crimestoppers anonymously on 0800 555 111 or report it online.
The incident comes only a week after another teenager was stabbed in Worthing town centre.
A 16-year-old boy was taken to hospital with potentially life-threatening injuries.
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