A woman was taken to hospital with serious injuries following a crash involving at least six cars.
Emergency services were called to the incident in Saddlescombe Road near Devil’s Dyke after snow and ice caused a number of vehicles to slip off the road into a neighbouring field.
One person was understood to be trapped during the crash.
A woman from Hove, who is in her 40s, has been taken to hospital with serious injuries following the crash.
Both Saddlescombe Road and Devil’s Dyke Road have been closed overnight and will remain closed while the vehicles involved are recovered.
A spokesman for Sussex Police said: “A woman in her 40s, from Hove, was taken to hospital with serious injuries.
“Saddlescombe Road and Devil’s Dyke Road remain closed in both directions awaiting the recovery of the affected vehicles.
"The incident is being investigated by the Surrey and Sussex Roads Policing Unit. Both roads are likely to be closed for some time.”
Cars involved in the crash were seen strewn across snow-covered fields following the incident.
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The crash comes after snow hit Sussex and causing traffic chaos across the county. Some drivers were forced to abandon their vehicles due to the weather conditions.
Multiple cars were involved in the crash as reports suggest between six and eight cars are thought to have been involved.
A spokeswoman from East Sussex Fire and Rescue said that four pumps were called to the scene of the crash at around 3.12pm on Sunday, December 11.
She added: "Crews successfully rescued the casualty from their vehicle and handed the casualty over to the care of South East Coast Ambulance Service."
Roads across Brighton and Sussex have been affected by the snow after the Met Office released a yellow weather warning for ice across the region.
Cars struggled to travel due to the conditions with traffic at a standstill in places due to the treacherous weather conditions.
Motorists have been urged to take precautions while driving and only to travel if necessary. Disruption has also been caused to public transport including buses and train services.
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