Brighton couple rejoice as drug saves dog from cancer death

Amanda and Terry Beadle, from Brighton, believed their dog would soon die from a rare kind of lymphoma.

Their beloved pet, Smithy, was initially diagnosed with lymphoma in 2018 and in remission until the lump returned in May last year.

Vets put the 12-year-old Portuguese water dog on steroids and palliative care as his condition worsened and the cancer continued to spread.

But in a last-ditch effort to save Smithy’s life, they tried a cancer drug called Verdinexor.

“He was prescribed a new-to-the-market drug and, happily, Smithy’s cancer now seems to be back under control,” said Amanda.

“He is still a bit wobbly from his arthritis but otherwise is enjoying life again and being back in the water, so we’re very grateful.”

Amanda and Smithy

Lymphoma is a cancer of the immune system, with many types proving fatal in a few weeks if untreated.

Vets will usually prescribe steroids to extend life by a few weeks, while chemotherapy can add months to life expectancy.

Smithy is now on the path back to full health after suffering from extreme weakness and hair loss.

And Gerry Polton, director of oncology at North Downs Specialists Referrals in Surrey where Smithy was treated, said it is thanks to the “first in class” drug Verdinexor.

“It is an oral treatment given twice a week by the owner at home, and the recent case of Smithy is a fine example of how well it can work,” said Gerry.

“Smithy had an unusual kind of lymphoma which can be best treated surgically. After a long period of remission, sadly, he suffered a recurrence of the lymphoma.

Smithy is now back enjoying regular dips in the water

“The prognosis was not good. He had been started on steroids and palliative care by his local vet, as his owners didn’t want Smithy to undergo chemo.

“Unfortunately, he developed a terrible skin complaint as a result of the steroids, and on top of this his lymphoma progressed so he was referred to us for specialist care and treatment.

“We reduced, and then withdrew, his steroids and started him on the Verdinexor and the transformation was dramatic.

“He looks really young again and is now back to doing his favourite thing – swimming in the lake.”