The NUT and NASUWT unions say their members have been forced to take action after talks with the Government broke down.
But the move has been criticised by some parents, who will have to take time off work or fork out for childcare as a result.
What do you think? Are the teachers right to strike? Or will the walkout cause too much disruption to people who are not to blame?
Have your say below, or by using the #sussexschoolstrike hashtag on Twitter.
Click here for our special Sussex School Strike news section.
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